NCAA
| Year | Coach | Round/Opponent | Result |
| 2007-08 | Danny Young | First- Hope College | L, 76-47 |
| 2010-11 | Danny Young-Uhrich |
First- Gallaudet Second-Greensboro College |
W, 62-45 L, 57-55 |
| 2011-12 | Danny Young-Uhrich |
First-Castleton Second- York College |
W, 84-57 L, 90-81 |
| 2017-18 | Danny Young-Uhrich |
First- Piedmont College Second- Thomas More College |
W, 63-52 L, 83-50 |
ECAC
| Year | Coach | Round/Opponent | Result |
| 2008-09 | Danny Young |
First- Albright College Semifinal- Alvernia Championship- Wesley |
W, 77-56 W, 80-72 W, 72-52 |
| 2009-10 | Danny Young-Uhrich |
First- Delaware Valley Semifinal- Widener Championship- Saint Vincent |
W, 67-65 W, 80- 74 L, 60-58 |
| 2012-13 | Danny Young-Uhrich |
First- Carnegie Mellon Semifinal- Moravian |
W, 94-80 L, 68-64 |
Landmark Conference
| Year | Coach | Round/Opponent | Result |
| 2007-08 | Danny Young |
Semifinal- Moravian Championship- Scranton |
W, 61-59 L, 52-50 |
| 2008-09 | Danny Young | Semifinal- Moravian | L, 66-57 |
| 2009-10 | Danny Young-Uhrich | Semifinal- Scranton | L, 70-62 |
| 2010-11 | Danny Young-Uhrich |
Semifinal- Catholic Championship- Scranton |
W, 74-61 W, 67-49 |
| 2011-12 | Danny Young-Uhrich |
Semifinal- Moravian Championship- Catholic |
W, 71-60 L, 79-69 |
| 2012-13 | Danny Young-Uhrich | Semifinal- Catholic | L, 72-59 |
| 2013-14 | Danny Young-Uhrich | Semifinal- Scranton | L, 74-53 |
| 2017-18 | Danny Young-Uhrich |
Semifinal- Elizabethtown Championship- Scranton |
W, 78-55 L(OT), 59-58 |
| 2020-21 | Danny Young-Uhrich |
Play In Game-Moravian |
L, 73-69 |
MAC
| Year | Coach | Opponent | Result |
| 1974-75 | Ed Gargula |
Albright Ursinus |
W, 37-35 L, 52-41 |
| 1975-76 | Ed Gargula |
Gettysburg Drew Scranton |
L, 45-43 W, 62-33 L, 61-47 |
| 1976-77 | Ed Gargula |
Wilkes Franklin & Marshall Widener |
W, 50-49 L, 47-39 W, 45-55 |
| 1977-78 | Nancy Latimore |
Albright Gettysburg Wilkes Albright |
L, 61-55 W, 67-39 W, 76-59 L, 47-44 |
| 1979-80 | Nancy Latimore |
Wilkes Scranton Widener |
W, 88-63 L, 68-61 W, 71-64 |
| 1990-91 | Kathi Quinn |
Elizabethtown |
L, 63-54 |
| 1991-92 | Kathi Quinn/ Stan Risser |
Scranton Susquehanna |
W, 71-65 L, 80-83 |
| 1993-94 | Stan Risser | Upsala | L, 93-64 |
| 1999-00 | Amy Buxbaum | Scranton | L, 77-58 |
| 2001-02 | Amy Buxbaum | Lebanon Valley | L, 61-54 |
